Preheat your oven to 350°F. Grease a 9×13 baking dish and set aside.
In a skillet over medium-high heat, cook the ground beef until browned and crumbly. Drain excess fat.
Add diced tomatoes, tomatoes with green chiles, tomato paste, garlic powder, onion powder, salt, and pepper. Simmer 15–20 minutes, stirring occasionally.
Meanwhile, cook the egg noodles according to package instructions until al dente. Drain and toss with sour cream until fully coated.
Spread the creamy noodles evenly in the baking dish. Pour the beef mixture over the noodles.
Sprinkle the shredded cheeses (cheddar, mozzarella, parmesan) evenly over the top.
Bake 20–25 minutes until hot, bubbly, and the cheese is melted and lightly browned.
Let stand 5 minutes before serving. Enjoy!